Indian Journal of PsychiatryIndian Journal of Psychiatry
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ARTICLE
Year : 1992  |  Volume : 34  |  Issue : 2  |  Page : 128-132

Heterogeneity in Plasma Homovanillic Acid Levels in Schizophreniform Disorder


1 Department of Psychopharmacology, National Institute of Mental Health & Neurosciences, Bangalore -560 029, India
2 Department of Psychiatry, Command Hospital, Air Force, Bangalore, India

Correspondence Address:
N Pradhan
Department of Psychopharmacology, National Institute of Mental Health & Neurosciences, Bangalore -560 029
India
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Source of Support: None, Conflict of Interest: None


PMID: 21776112

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Plasma homovanillic acid (pHVA) levels were estimated in 20 cases of schizophreniform disorder, 14 cases of schizophrenia 'on medication' and 17 cases of schizophrenia 'off medication'. A bimodal distribution of pHVA was seen in schizophreniform disorder subjects, suggesting heterogenous groups in terms of dopaminergic function. No significant difference in the pHVA values was seen in the 3 groups, nor was there a relationship between the severity of the illness and the pHVA values; these results suggest plasticity of the dopaminergic system to neuroleptics.



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