Indian Journal of PsychiatryIndian Journal of Psychiatry
Home | About us | Current Issue | Archives | Ahead of Print | Submission | Instructions | Subscribe | Advertise | Contact | Login 
    Users online: 1819 Small font sizeDefault font sizeIncrease font size Print this article Email this article Bookmark this page
Search Again
 Back
 Table of Contents
 
 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Article Access Statistics
 Reader Comments
 Email Alert
 Add to My List
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed394    
    Printed29    
    Emailed0    
    PDF Downloaded27    
    Comments [Add]    

Recommend this journal

 
ARTICLE
Year : 1997  |  Volume : 39  |  Issue : 4  |  Page : 272-277

ECT and Platelet 5 HT Uptake in Major Depression


1 Associate Professor, Department of Psychiatry, K.G'S Medical College, Lucknow-226003, India
2 Professor, Department of Psychiatry, K.G'S Medical College, Lucknow-226003, India
3 Director, Department of Psychiatry, K.G'S Medical College, Lucknow-226003, India
4 Scientist, Department of Psychiatry, K.G'S Medical College, Lucknow-226003, India
5 Senior Resident, Department of Psychiatry, K.G'S Medical College, Lucknow-226003, India

Correspondence Address:
P K Dalal
Associate Professor, Department of Psychiatry, K.G'S Medical College, Lucknow-226003
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


PMID: 21584091

Rights and PermissionsRights and Permissions

Several studies have reported decreased platelet 5-HT uptake in patients of major depression. The mechanism of antidepressant action of ECT is not clear. The present work was undertaken with the aim to study the active platelet 5-HT uptake and the effect of ECT on it in patients of major depression. 15 patients of major depression (DSM-lll-R) and equal number of age and sex-matched controls were included in the study. Active platelet 5-HT uptake was determined before ECT, after a course of ECT and 7 days after last ECT. Platelet 5-HT uptake was. significantly lower in der essives than normal controls. After ECT treatment there was significant increase in 5-HT uptake which came down to pretreatment level after 1 week of last ECT. The effect of ECT on serotonergic system is discussed.



[PDF]*

        

Print this article         Email this article