Indian Journal of PsychiatryIndian Journal of Psychiatry
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ARTICLE
Year : 1998  |  Volume : 40  |  Issue : 2  |  Page : 180-185

Neurological Soft Signs, Cognitive Dysfunction and Ventricular Brain Ration in Schizophrenics


1 Professor, Department of Psychiatry, K.G. Medical College, Lucknow, India
2 Associate Professor, Department of Psychiatry, K.G. Medical College, Lucknow, India
3 Senior Resident, Department of Psychiatry, K.G. Medical College, Lucknow, India
4 Ex-Resident, Department of Psychiatry, K.G. Medical College, Lucknow, India
5 Associate Professor, Department of Radiodiagnosis, K.G. Medical College, Lucknow, India

Correspondence Address:
Narottam Lal
Professor, Department of Psychiatry, K.G. Medical College, Lucknow
India
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Source of Support: None, Conflict of Interest: None


PMID: 21494466

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An association between cognitive dysfunction, neurological soft signs, enlarged brain ventricles and widened cortical sulci has been reported in schizophrenia. The present work aimed to study the relevance of positive and negative dichotomy with relation to neuropsychological performance of the schizophrenic patients, and the presence of neurological soft signs. In 23 schizophrenics patients diagnosed according to DSM-III-R of which 14 were of positive subtype and 9 were of negative subtype. At least one neurological soft sign was present in all the patients. The positive group had higher WMS and IQ scores and lower BGT scores than the negative group. Negative, correlation was seen for WMS and BGT scores with Ventricular Brain Ratio (VBR), and the.' soft signs showed positive correlation in the positive subtype only.



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