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ARTICLE
Year : 2000  |  Volume : 42  |  Issue : 1  |  Page : 94-97

Valproate in Acute Mania - A Controlled Study


1 Senior Research Fellow, Department of Psychiatry, NIMHANS, Bangalore-560 029, India
2 Associate Professor, Department of Psychiatry, NIMHANS, Bangalore-560 029, India

Correspondence Address:
H M Prakash
Senior Research Fellow, Department of Psychiatry, NIMHANS, Bangalore-560 029
India
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Source of Support: None, Conflict of Interest: None


PMID: 21407916

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A controlled blind study was carried out to establish the efficacy of Sodium Valproate as the first line of treatment in Acute Mania. Patients were studied over a period of 4 weeks. Using randomised table patients were assigned to either lithium or valproate. Decrease in the psychopathology was evident within 2-3 weeks. Valproate was found to be as effective as Lithium in controlling the manic episode.



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