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ARTICLE
Year : 2000  |  Volume : 42  |  Issue : 3  |  Page : 275-279

Role of HLA Class-I Antigens in Delusional Disorder


1 Junior Research Fellow, Cellular Immunology Lab , Department of Zoology, North Bengal University, Siliguri, West Bengal, India
2 Professor & Head, Department of Psychiatry, North Bengal University, Siliguri, West Bengal, India
3 Senior Research Fellow, Cellular Immunology Lab., Department of Zoology, North Bengal University, Siliguri, West Bengal, India
4 Reader & Incharge, Cellular Immunology Lab., Department of Zoology, North Bengal University, Siliguri, West Bengal, India

Correspondence Address:
Tapas K Chaudhuri
Reader & Incharge, Cellular Immunology Lab., Department of Zoology, North Bengal University, Siliguri, West Bengal
India
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Source of Support: None, Conflict of Interest: None


PMID: 21407957

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The investigation was conducted to find out whether there is any association between delusional disorder and HLA antigens. The sample comprised 50 patients with delusional disorder and 282 control samples collected from normal controls. Statistical analysis revealed that the frequency of A3 antigen of the locus A are significantly higher. In case of HLA - B locus significantly higher frequency of B5 and B21 antigens have also been observed. The present study shows that there may be some association of HLA class-1 antigens with delusional disorder.



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