Indian Journal of PsychiatryIndian Journal of Psychiatry
Home | About us | Current Issue | Archives | Ahead of Print | Submission | Instructions | Subscribe | Advertise | Contact | Login 
    Users online: 2398 Small font sizeDefault font sizeIncrease font size Print this article Email this article Bookmark this page
Search Again
 Back
 Table of Contents
 
 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Article Access Statistics
 Reader Comments
 Email Alert
 Add to My List
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed581    
    Printed32    
    Emailed0    
    PDF Downloaded71    
    Comments [Add]    

Recommend this journal

 
ARTICLE
Year : 2000  |  Volume : 42  |  Issue : 4  |  Page : 410-414

Long Term Effects of Lithium on Glomerular Filtration Rate in Indian Subjects - A Cross Sectional Study


1 Assistant Professor, Department of Nuclear Medicine, PGlMER, Chandigarh -160012, India
2 Assistant Professor, Department of Nephrology, PGlMER, Chandigarh -160012, India
3 Assistant Professor, Department of Psychiatry, PGlMER, Chandigarh -160012, India
4 Professor, Department of Nuclear Medicine, PGlMER, Chandigarh -160012, India

Correspondence Address:
Baljinder Singh
Assistant Professor, Department of Nuclear Medicine, PGlMER, Chandigarh -160012
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


PMID: 21407979

Rights and PermissionsRights and Permissions

Glomerular filtration rate (GFR) was evaluated in thirty patients on lithium and in thirty healthy prospective kidney donors by single compartment, multiple sample plasma clearance method using 99m Technetium diethylene triamine pentaacetic acid ( 99m TC-DTPA). Normality test revealed that dose and treatment duration were skewed and the coefficient of skewness were 0.067 (p<0.0001) and 1.41 (p<0.0001) respectively. Age was marginally skewed (p =0.04) for the control group. At 5% significance level, dose and creatinine were negatively correlated (r=-0.030), whereas age and duration were positively correlated (r =+ 0.53) (single tailed only). Duration and GFR seems to be negatively correlated (r = -0.23), however this correlation did not reach statistically significance level. In the present cross sectional study no significant difference in mean GFR was observed in lithium treated affective disorder patients when compared with the age matched normal subjects.



[PDF]*

        

Print this article         Email this article