|Year : 2009 | Volume
| Issue : 4 | Page : 272-275
Clinical practice with antidementia and antipsychotic drugs: Audit from a geriatric clinic in India
Krishna Prasad1, Himanshu Gupta1, Srikala Bharath1, Om Prakash2, PT Sivakumar1, C Naveen Kumar1, Mathew Varghese1
1 Geriatric Clinic and Services, Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore - 560 029, India
2 Department of Psychiatry, Institute of Human Behaviour & Allied Sciences, Delhi - 110 095, India
Background: Dementia is one of the most disabling disorders afflicting the elderly, with a staggering emotional and economic impact. Antidementia agents have been used for delaying cognitive decline. Antipsychotics are commonly prescribed for behavioral symptoms associated with dementia.
Objectives: To explore the use of anti-dementing agents and antipsychotics used in patients with a diagnosis of dementia
Materials and Methods: A retrospective chart review method; geriatric clinic of tertiary care setting.
Results: The study sample included 51 consecutive patients with a diagnosis of dementia. The commonest subtype of dementia that was diagnosed was Alzheimer's disease (45%), followed by Frontotemporal dementia (25%).The commonest antidementia drug that was used was donepezil, which alone was prescribed in 27 patients (52%). The commonest antipsychotic used was quetiapine, which was used in 24 patients (47%).
Conclusions: The study found donepezil to be the most commonly prescribed antidementia drug and quetiapine to be the most commonly used antipsychotic in a tertiary care geriatric clinic, in a developing country. There is a need to study the cost-effectiveness of antidementia and antipsychotic drugs in patients with dementia, in developing countries.
Department of Psychiatry, Institute of Human Behaviour & Allied Sciences (IHBAS), Dilshad Garden, Delhi - 110 095
Source of Support: None, Conflict of Interest: None
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