Indian Journal of PsychiatryIndian Journal of Psychiatry
Home | About us | Current Issue | Archives | Ahead of Print | Submission | Instructions | Subscribe | Advertise | Contact | Login 
    Users online: 722 Small font sizeDefault font sizeIncrease font size Print this article Email this article Bookmark this page
Search Again
 Back
 Table of Contents
 
 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Article Access Statistics
 Reader Comments
 Email Alert
 Add to My List
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed3419    
    Printed221    
    Emailed4    
    PDF Downloaded478    
    Comments [Add]    
    Cited by others 7    

Recommend this journal

 
REVIEW ARTICLE
Year : 2010  |  Volume : 52  |  Issue : 2  |  Page : 127-130

A tale of two comorbidities: Understanding the neurobiology of depression and pain


1 Research and Scientific Initiatives, Department of Neuropsychiatry and Behavioral Science, University of South Carolina School of Medicine
2 General Psychiatry Training Program, Department of Neuropsychiatry and Behavioral Science, University of South Carolina School of Medicine

Correspondence Address:
Meera Narasimhan
Research and Scientific Initiatives, Department of Neuropsychiatry and Behavioral Science, University of South Carolina School of Medicine, Suite 301, 3555 Harden Street Extension, Columbia, SC-29203

Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0019-5545.64586

Rights and Permissions

The comorbidity of chronic pain and depression has been consistently associated with a poor prognosis and greater disability in patients as compared to those suffering from each illness alone. This further has implications on significant financial costs to the patients and to our society. The biological underpinnings of major depression and chronic pain have considerable overlap in the areas of genetic, structural, functional, neuroendocrine and neurotransmitter functionality. Although the field has evolved in the past decade, more efforts should now focus on understanding the biological underpinnings of this shared comorbidity, while shedding light on treatment implications for these two devastating conditions.



[FULL TEXT] [PDF]*

        

Print this article         Email this article