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CASE REPORT
Year : 2011  |  Volume : 53  |  Issue : 2  |  Page : 163-165

Glaucoma: Adverse event on use of topiramate in alcohol de-addiction


Department of Psychiatry, Kasturba Medical College, Attavara, Mangalore, Karnataka, India

Correspondence Address:
Keshava Pai
Department of Psychiatry, Kasturba Medical College Hospital, Attavara, Mangalore - 576001, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0019-5545.82552

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To report oral topiramate-induced glaucoma and to asses its severity and preventability. A 40-year-old manpresented with watering, redness, pain, and diminution of vision of both eyes, one week after initiation of oral topiramate 100 mg/day for alcohol de-addiction. On examination, both eyes showed conjunctival chemosis, corneal edema, shallow anterior chamber, and intraocular pressure 48 and 46 mm Hg. The symptoms and clinical findings resolved completely upon discontinuation of topiramate and administration of antiglaucoma drugs. Topiramate-induced angle-closure glaucoma and other ocular side effects are reversible if the diagnosis is made early and the drug is discontinued in time. Hence, clinician awareness is an important aspect of preventability of this adverse event.



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