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|Year : 2014 | Volume
| Issue : 3 | Page : 253-264
Indian Psychiatric Society multicentric study: Prescription patterns of psychotropics in India
Sandeep Grover1, Ajit Avasthi1, Vishal Sinha2, Bhavesh Lakdawala3, Manish Bathla4, Sujata Sethi5, DM Mathur6, Puneet Kathuria7, Sandip Shah8, D Sai Baalasubramanian9, Vivek Agarwal10, Kamla Deka11
1 Department of Psychiatry, PGIMER, Chandigarh, India
2 Department of Psychiatry, S N Medical College, Agra, Uttar Pradesh, India
3 Department of Psychiatry, B J Medical College and Civil Hospital, Ahmedabad, Gujarat, India
4 Department of Psychiatry, MM Institute of Medical Sciences and Research, Mullana, Ambala, India
5 Department of Psychiatry, PGIMS, Rohtak, India
6 Department of Psychiatry, Gitanjali Medical College Hospital, Udaipur, Rajasthan, India
7 Consultant Psychiatrist, Ludhiana, Punjab, India
8 SBKS MI & RC, Sumandeep Vidyapeeth, Pipaira, Vadodara, Gujarat, India
9 SRM Medical College Hospital and Research Centre, Chennai, Tamil Nadu, India
10 KGMU, Lucknow, Uttar Pradesh, India
11 Guwahati Medical College, Guwahati, Assam, India
Background: There is a lack of national level data from India on prescription of psychotropics by psychiatrists.
Aim and Objective: This study aimed to assess the first prescription handed over to the psychiatrically ill patients whenever they contact a psychiatrist.
Materials and Methods: Data were collected across 11 centers. Psychiatric diagnosis was made as per the International Classification of Diseases Classification of Mental and Behavioural Disorders 10 th edition criteria based on Mini International Neuropsychiatric Interview, and the data of psychotropic prescriptions was collected.
Results: Study included 4480 patients, slightly more than half of the subjects were of male (54.8%) and most of the participants were married (71.8%). Half of the participants were from the urban background, and about half (46.9%) were educated up to or beyond high school. The most common diagnostic category was that of affective disorders (54.3%), followed by Neurotic, stress-related and somatoform disorders (22.2%) and psychotic disorders (19.1%). Other diagnostic categories formed a very small proportion of the study participants. Among the antidepressants, most commonly prescribed antidepressant included escitalopram followed by sertraline. Escitalopram was the most common antidepressant across 7 out of 11 centers and second most common in three centers. Among the antipsychotics, the most commonly prescribed antipsychotic was olanzapine followed by risperidone. Olanzapine was the most commonly prescribed antipsychotic across 6 out of 11 centers and second most common antipsychotic across rest of the centers. Among the mood stabilizers valproate was prescribed more often, and it was the most commonly prescribed mood stabilizer in 8 out of 11 centers. Clonazepam was prescribed as anxiolytic about 5 times more commonly than lorazepam. Clonazepam was the most common benzodiazepine prescribed in 6 out of the 11 centers. Rate of polypharmacy was low.
Conclusion: Escitalopram is the most commonly prescribed antidepressant, olanzapine is the most commonly prescribed antipsychotic and clonazepam is most commonly prescribed benzodiazepine. There are very few variations in prescription patterns across various centers.
Dr. Sandeep Grover
Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh - 160 012
Source of Support: This study was funded by Indian Psychiatric Society (Funded amount- 1.2 lakhs),, Conflict of Interest: None
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