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 Table of Contents    
LETTERS TO EDITOR  
Year : 2018  |  Volume : 60  |  Issue : 2  |  Page : 257
A possible role for ketamine in suicide prevention in emergency and mainstream psychiatry


1 Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India
2 Department of Psychiatry, National Institute of Mental Health and Neurosciences, Center for Addiction Medicine, Bengaluru, Karnataka, India

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Date of Web Publication17-Aug-2018
 

How to cite this article:
Suhas S, Shukla L. A possible role for ketamine in suicide prevention in emergency and mainstream psychiatry. Indian J Psychiatry 2018;60:257

How to cite this URL:
Suhas S, Shukla L. A possible role for ketamine in suicide prevention in emergency and mainstream psychiatry. Indian J Psychiatry [serial online] 2018 [cited 2018 Oct 16];60:257. Available from: http://www.indianjpsychiatry.org/text.asp?2018/60/2/257/239134




Sir,

We read with interest the editorial on a possible role for ketamine in suicide prevention in emergency and mainstream psychiatry.[1] The editorial cited a meta-analysis [2] that included five studies. One of these five studies [3] used a single question from the Montgomery–Asberg Depression Rating Scale to assess change in suicidal ideation; the rest, in contrast, used a separate suicidal ideation scale. More importantly, this study [3] was retracted in July 2017[4] because it supposedly misrepresented both the protocol-specified doses and the actual-delivered doses of ketamine in the study.

We wonder how much the findings of the meta-analysis [2] would change were the retracted data [3] to be removed; and whether the message in the editorial would be moderated, in consequence.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.



 
   References Top

1.
Sathyanarayana Rao TS, Andrade C. A possible role for ketamine in suicide prevention in emergency and mainstream psychiatry. Indian J Psychiatry 2017;59:259-61.  Back to cited text no. 1
    
2.
Bartoli F, Riboldi I, Crocamo C, Di Brita C, Clerici M, Carrà G, et al. Ketamine as a rapid-acting agent for suicidal ideation: A meta-analysis. Neurosci Biobehav Rev 2017;77:232-6.  Back to cited text no. 2
    
3.
Larkin GL, Beautrais AL. A preliminary naturalistic study of low-dose ketamine for depression and suicide ideation in the emergency department. Int J Neuropsychopharmacol 2011;14:1127-31.  Back to cited text no. 3
    
4.
Larkin GL, Beautrais AL. A preliminary naturalistic study of low-dose ketamine for depression and suicide ideation in the emergency department. Int J Neuropsychopharmacol 2017;20:611.  Back to cited text no. 4
    

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Correspondence Address:
Satish Suhas
Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/psychiatry.IndianJPsychiatry_1_18

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