Indian Journal of PsychiatryIndian Journal of Psychiatry
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CASE REPORT
Year : 2019  |  Volume : 61  |  Issue : 1  |  Page : 94-96

Leukocytoclastic vasculitis secondary to clozapine


1 Department of Clinical and Experimental Pharmacology, School of Tropical Medicine, Kolkata, West Bengal, India
2 Department of Pharmacology, MGM Medical College and LSK Hospital, Kishanganj, Bihar, India
3 Department of Pathology, MGM Medical College and LSK Hospital, Kishanganj, Bihar, India

Correspondence Address:
Shatavisa Mukherjee
Department of Clinical and Experimental Pharmacology, School of Tropical Medicine, Kolkata - 700 073, West Bengal
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/psychiatry.IndianJPsychiatry_384_18

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Leukocytoclastic vasculitis (LCV) may be secondary to drugs, underlying infection, collagen vascular disorders, or malignancy. Drug-induced vasculitis contributes to 10% of vasculitic skin lesions cases usually developing within 7–21 days of treatment initiation. The present case highlights a report of LCV in a 59-year-old male with a history of paranoid schizophrenia on clozapine therapy. The report upsurges the need to promote awareness and expedite diagnosis and treatment of drug-induced LCVs.



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