Year : 1996  |  Volume : 38  |  Issue : 1  |  Page : 47--50

Adverse Effects of Disulfiram and Patient Compliance


TN Srinivasan1, TR Suresh2, Jayaram Vasantha3 
1 Psychiatrist, Sundaram Medical Frundation, Madras - 600 040, India
2 Psychiatrist, Vijaya Hospital, Madras - 600 026, India
3 Psychiatrist, 2nd Street, Srinivasapuram, Tiruvanmiyur, Madras - 600 041, India

Correspondence Address:
T N Srinivasan
Psychiatrist, Sundaram Medical Frundation, Madras - 600 040
India

Use of Disulfiram under supervision in well-motivated alcoholics is effective in reducing relapse rates. Several adverse effects, some of them life-threatening, have been reported due to the drug. An awareness of the adverse effects is useful to keep a follow up and sustain patient compliance with the drug. This study of 158 out patients on daily oral disulfiram revealed that though many patients report unpleasant effects most of them could not be distinguished from symptoms of alcoholism present before taking disulfiram and hence cannot be considered as adverse effects of the drug. The actual adverse symptoms were also mild and could be easily managed and were infrequent and not the common cause for poor patient compliance. The study suggests that Disulfiram with its low toxicity can be offered to patients without too much reservation.


How to cite this article:
Srinivasan T N, Suresh T R, Vasantha J. Adverse Effects of Disulfiram and Patient Compliance.Indian J Psychiatry 1996;38:47-50


How to cite this URL:
Srinivasan T N, Suresh T R, Vasantha J. Adverse Effects of Disulfiram and Patient Compliance. Indian J Psychiatry [serial online] 1996 [cited 2019 Dec 10 ];38:47-50
Available from: http://www.indianjpsychiatry.org/article.asp?issn=0019-5545;year=1996;volume=38;issue=1;spage=47;epage=50;aulast=Srinivasan;type=0