Year : 2000  |  Volume : 42  |  Issue : 1  |  Page : 48--51

Serum Prolactin Level and Severity of Psychopathology in Patients of Schizophrenia


Amresh Shrivastava1, Manoj Tamhane2 
1 Consultant Psychiatrist, Silver Mind Hospital, 209, Shivkripa Complex, Gokhle Road, Thane, Mumbai-400 602, India
2 Consultant, Immuno Pathologist, Silver Mind Hospital, 209, Shivkripa Complex, Gokhle Road, Thane, Mumbai-400 602, India

Correspondence Address:
Amresh Shrivastava
Consultant Psychiatrist, Silver Mind Hospital, 209, Shivkripa Complex, Gokhle Road, Thane, Mumbai-400 602
India

Serum prolactin level was measured in 20 male and 11 female drug naive patients of schizophrenia Subsequently, these patients were treated with antipsychotics and ECTs. The severity of psychopathology at the baseline rind subsquent improvement at the end of 3 weeks and 6 weeks was assessed on modifies brief psychiatric rating scale (BPRS). Contrary to the expectations, a two fold increase in serum prolactin level was observed in drug naive male and female patients of schizophrenia The difference was found to be statictically significant in males No correlation was observed between the baseline serum prolactin level and the severity of baseline psychopathology and subsequent improvement in psychopathology at the end of 3 weeks and 6 weeks From the present study it seems that baseline serum prolactine level in drug naοve patients of schizophrenia may not be a reliable indicator of psychopathology and prognosis.


How to cite this article:
Shrivastava A, Tamhane M. Serum Prolactin Level and Severity of Psychopathology in Patients of Schizophrenia.Indian J Psychiatry 2000;42:48-51


How to cite this URL:
Shrivastava A, Tamhane M. Serum Prolactin Level and Severity of Psychopathology in Patients of Schizophrenia. Indian J Psychiatry [serial online] 2000 [cited 2020 Sep 25 ];42:48-51
Available from: http://www.indianjpsychiatry.org/article.asp?issn=0019-5545;year=2000;volume=42;issue=1;spage=48;epage=51;aulast=Shrivastava;type=0