Year : 2009  |  Volume : 51  |  Issue : 3  |  Page : 202--205

Prevalence of neuroleptic malignant syndrome in 672 consecutive male in-patients


Pradyot Sarkar1, Chandrashekhar Natarajan1, Neeta Gode2 
1 Department of Psychiatry, Command Hospital, Alipore, Kolkata, West Bengal, India
2 Military Hospital, Jhansi, UP, India

Correspondence Address:
Pradyot Sarkar
Department of Psychiatry, Command Hospital (EC), Alipore, Kolkata - 700 027
India

Background: Neuroleptic malignant syndrome (NMS) is the most serious and potentially fatal adverse effect of neuroleptic medications. Although it occurs most frequently with conventional antipsychotic medicines, it may occur with newer antipsychotic medicines also. So far, there is no study available about the prevalence of this condition in the Indian population. Aim: To find the prevalence of NMS in the Indian population . Materials and Methods: A total of 672 consecutive male patients who were hospitalized with psychotic breakdowns and treated with neuroleptics were screened for evidence of the development of NMS, clinically, and supported by laboratory investigations. Results: Three patients, all suffering from manic episode, developed NMS within few days of initiation of neuroleptic medicines. Haloperidol injection was given in all three cases . Conclusion: The prevalence of NMS was 0.45%. All were young males, suffering from manic episode with psychotic symptoms and managed with oral and parentral neuroleptic medicines.


How to cite this article:
Sarkar P, Natarajan C, Gode N. Prevalence of neuroleptic malignant syndrome in 672 consecutive male in-patients.Indian J Psychiatry 2009;51:202-205


How to cite this URL:
Sarkar P, Natarajan C, Gode N. Prevalence of neuroleptic malignant syndrome in 672 consecutive male in-patients. Indian J Psychiatry [serial online] 2009 [cited 2019 Sep 22 ];51:202-205
Available from: http://www.indianjpsychiatry.org/article.asp?issn=0019-5545;year=2009;volume=51;issue=3;spage=202;epage=205;aulast=Sarkar;type=0