Year : 2010  |  Volume : 52  |  Issue : 7  |  Page : 120--127

Molecular biology research in neuropsychiatry: India«SQ»s contribution

T. S. Sathyanarayana Rao1, BN Ramesh2, P Vasudevaraju2, K. S. J. Rao2 
1 Department of Psychiatry, JSS Medical College, JSS University, Mysore, India
2 Biochemistry and Nutrition, CFTRI, CSIR Unit, Mysore, India

Correspondence Address:
T. S. Sathyanarayana Rao
Department of Psychiatry, JSS Medical college, JSS University, Mysore

Neuropsychiatric disorders represent the second largest cause of morbidity worldwide. These disorders have complex etiology and patho-physiology. The major lacunae in the biology of the psychiatric disorders include genomics, biomarkers and drug discovery, for the early detection of the disease, and have great application in the clinical management of disease. Indian psychiatrists and scientists played a significant role in filling the gaps. The present annotation provides in depth information related to research contributions on the molecular biology research in neuropsychiatric disorders in India. There is a great need for further research in this direction as to understand the genetic association of the neuropsychiatric disorders; molecular biology has a tremendous role to play. The alterations in gene expression are implicated in the pathogenesis of several neuropsychiatric disorders, including drug addiction and depression. The development of transgenic neuropsychiatric animal models is of great thrust areas. No studies from India in this direction. Biomarkers in neuropsychiatric disorders are of great help to the clinicians for the early diagnosis of the disorders. The studies related to gene-environment interactions, DNA instability, oxidative stress are less studied in neuropsychiatric disorders and making efforts in this direction will lead to pioneers in these areas of research in India. In conclusion, we provided an insight for future research direction in molecular understanding of neuropsychiatry disorders.

How to cite this article:
Rao TS, Ramesh B N, Vasudevaraju P, Rao K. Molecular biology research in neuropsychiatry: India's contribution.Indian J Psychiatry 2010;52:120-127

How to cite this URL:
Rao TS, Ramesh B N, Vasudevaraju P, Rao K. Molecular biology research in neuropsychiatry: India's contribution. Indian J Psychiatry [serial online] 2010 [cited 2020 Jul 14 ];52:120-127
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