Year : 2012  |  Volume : 54  |  Issue : 1  |  Page : 88--90

Klinefelter俟Q製 syndrome (mosaic) with chromosome 9 inv and schizophrenia


R Ponnudurai1, B Srinivasan1, R Sumitha2, Teena Koshy3, Solomon S. D. Paul3, Thiruvikraman1, Anjana Rani1 
1 Department of Psychiatry, Sri Ramachandra University, Porur, Chennai, Tamil Nadu, India
2 Biomedical Science Technology and Research, Sri Ramachandra University, Porur, Chennai, Tamil Nadu, India
3 Department of Human Genetics, Sri Ramachandra University, Porur, Chennai, Tamil Nadu, India

Correspondence Address:
R Ponnudurai
24/3-B, T. T. K. Road, Chennai - 600 018
India

Klinefelter俟Q製 syndrome is a sex chromosome abnormality with low androgen level. The varied manifestations of the mental symptoms in some of them, that are inexplicable based on their genotype alone, has fascinated the researchers. We present here a case of Klinefelter俟Q製 syndrome having a karyotype of mos 47, XXY, and also inversion in 9 th chromosome, with schizophrenia. Despite the view that inv 9 is a normal variant, it is still worthwhile to explore whether it has any role in the etiology of schizophrenia especially when it occurs with other genotypic aberrations that are suspected to have relevance to psychiatric disorders including the Klinefelter俟Q製 syndrome.


How to cite this article:
Ponnudurai R, Srinivasan B, Sumitha R, Koshy T, Paul SS, Thiruvikraman, Rani A. Klinefelter's syndrome (mosaic) with chromosome 9 inv and schizophrenia.Indian J Psychiatry 2012;54:88-90


How to cite this URL:
Ponnudurai R, Srinivasan B, Sumitha R, Koshy T, Paul SS, Thiruvikraman, Rani A. Klinefelter's syndrome (mosaic) with chromosome 9 inv and schizophrenia. Indian J Psychiatry [serial online] 2012 [cited 2020 Apr 3 ];54:88-90
Available from: http://www.indianjpsychiatry.org/article.asp?issn=0019-5545;year=2012;volume=54;issue=1;spage=88;epage=90;aulast=Ponnudurai;type=0