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ARTICLE
Year : 1991  |  Volume : 33  |  Issue : 4  |  Page : 271-280

Clinical Variables and Platelet MAO in Schizophrenia


1 Paper presented at the " Marfatia award session" of the 42nd Annual Conference of Indian Psychiatric Society, India
2 Reader in Bio-Psychiatry, Institute of Medical Science Banaras Hindu University, Varanasi-221 005, India
3 Junior Resident Psychiatry- 5.Senior Resident Psychiatry-Department of Psychiatry, Institute of Medical Science Banaras Hindu University, Varanasi-221 005, India
4 Senior Research Officer-Department of Experimental Medicine and Surgery, Institute of Medical Science Banaras Hindu University, Varanasi-221 005, India

Correspondence Address:
Indira Sharma
Paper presented at the " Marfatia award session" of the 42nd Annual Conference of Indian Psychiatric Society
India
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Source of Support: None, Conflict of Interest: None


PMID: 21897470

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Platelet MAO activity was estimated in 60 male drug free schizophrenics and 26 controls matched for age. The paranoid group had significantly lower enzyme activity than the non-paranoid group and controls. Patients with premorbid schizoid personality had significantly lower enzyme activity than patients with non-schizoid premorbid personality and controls. A significant negative correlation between platelet MAO activity and severity and duration of illness was observed. Family history of schizophrenia, presence of auditory hallucinations and type and age of onset of illness were not related to platelet MAO activity.



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