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| Year : 1992 | Volume
: 34
| Issue : 3 | Page : 264-272 |
Multiple Endocrine Responses to Clonidine in Obsessive Compulsive Dissorder
Sumant Khanna1, PL Reddy2, MN Subhash2, B.S Sridhara Rama Rao2, SM Channabasavanna1
1 Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore - 560 029, India
2 Department of Biochemistry, National Institute of Mental Health and Neurosciences, Bangalore - 560 029, India
Correspondence Address:
Sumant Khanna
Assistant Professor, Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore - 560 029
India
 Source of Support: None, Conflict of Interest: None  | Check |
PMID: 21776130 
Seventy two subjects with OCD were compared with 18 normal healthy volunteers on multiple neuroendocrine responses to clonidine. Significant heterogeneity in OCD was observed in responses of growth hormone. There was also significant disturbances in Cortisol and ACTH release. An interactional model for noradrenergic and serotonergic dysfunction in OCD is discussed.
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