Indian Journal of PsychiatryIndian Journal of Psychiatry
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Year : 1996  |  Volume : 38  |  Issue : 4  |  Page : 208-211

The Psychiatric Aspects of Wilsons Disease - A Study from A Neurology Unit

1 Formerly in the Department of Psychiatry, Christian Medical College, Vellore - 632 002, India
2 Department of Biostatistics, Christian Medical College, Vellore - 632 002, India
3 Department of Neurological Science, Christian Medical College, Vellore - 632 002, India

Correspondence Address:
Rajeev Kumar
Royal Park Hospital, Private bag no 3, P.O. Parkville, Victoria 3052, Australia
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Source of Support: None, Conflict of Interest: None

PMID: 21584132

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A series of 31 cases of Wilson's disease (WD) were assessed retrospectively on a range of variables including psychiatric, neurologic and biochemical data recorded at index admission over a period of 7 years. 18 patients (58%) showed psychopathological features. 5 patients (16.1%) were reported to have poor scholastic performance at the onset of illness and 1 patient (3.2%) had abnormal behaviour (mania like) many years prior to the appearance of neurological symptoms. The most common psychiatric features were cognitive impairment (45.2%), affective symptomatology (41.9%) and behavioural abnormalities (29%). Only one patient had a schizophrenia like psychosis. The psychiatric manifestation of Wilson's disease as they present in our setting and their clinical relevance are discussed.



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