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Year : 2000 | Volume
: 42
| Issue : 1 | Page : 94-97 |
Valproate in Acute Mania - A Controlled Study
HM Prakash1, Srikala Bharath2
1 Senior Research Fellow, Department of Psychiatry, NIMHANS, Bangalore-560 029, India 2 Associate Professor, Department of Psychiatry, NIMHANS, Bangalore-560 029, India
Correspondence Address:
H M Prakash Senior Research Fellow, Department of Psychiatry, NIMHANS, Bangalore-560 029 India
 Source of Support: None, Conflict of Interest: None  | Check |
PMID: 21407916 
A controlled blind study was carried out to establish the efficacy of Sodium Valproate as the first line of treatment in Acute Mania. Patients were studied over a period of 4 weeks. Using randomised table patients were assigned to either lithium or valproate. Decrease in the psychopathology was evident within 2-3 weeks. Valproate was found to be as effective as Lithium in controlling the manic episode.
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