Indian Journal of PsychiatryIndian Journal of Psychiatry
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Year : 2000  |  Volume : 42  |  Issue : 2  |  Page : 167-171

Genomic Imprinting in Bipolar Affective Disorder

1 Resident, Department of Psychiatry, C.I.P., Ranchi, India
2 Associate Professor, Department of Psychiatry, C.I.P., Ranchi, India

Correspondence Address:
Ratanendra Kumar
"Jai Gurudev", Ratu Road, P.O. Hehal, Ranchi-834 005
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Source of Support: None, Conflict of Interest: None

PMID: 21407931

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With recent advances in molecular genetics, a new mechanism proposed for the inheritance of Bipolar Disorder is Genomic Imprinting or Parent of Origin Affect. In this study of 79 consecutive first episode manic patients, predominantly male, we failed to establish the phenomenon of imprinting. With other proposed non-Mendelian patterns of inheritance, it may be that bipolar disorder is genetically heterogenous.



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