Year : 2018  |  Volume : 60  |  Issue : 2  |  Page : 257-

A possible role for ketamine in suicide prevention in emergency and mainstream psychiatry


Satish Suhas1, Lekhansh Shukla2,  
1 Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India
2 Department of Psychiatry, National Institute of Mental Health and Neurosciences, Center for Addiction Medicine, Bengaluru, Karnataka, India

Correspondence Address:
Satish Suhas
Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka
India




How to cite this article:
Suhas S, Shukla L. A possible role for ketamine in suicide prevention in emergency and mainstream psychiatry.Indian J Psychiatry 2018;60:257-257


How to cite this URL:
Suhas S, Shukla L. A possible role for ketamine in suicide prevention in emergency and mainstream psychiatry. Indian J Psychiatry [serial online] 2018 [cited 2021 Sep 25 ];60:257-257
Available from: https://www.indianjpsychiatry.org/text.asp?2018/60/2/257/239134


Full Text



Sir,

We read with interest the editorial on a possible role for ketamine in suicide prevention in emergency and mainstream psychiatry.[1] The editorial cited a meta-analysis [2] that included five studies. One of these five studies [3] used a single question from the Montgomery–Asberg Depression Rating Scale to assess change in suicidal ideation; the rest, in contrast, used a separate suicidal ideation scale. More importantly, this study [3] was retracted in July 2017[4] because it supposedly misrepresented both the protocol-specified doses and the actual-delivered doses of ketamine in the study.

We wonder how much the findings of the meta-analysis [2] would change were the retracted data [3] to be removed; and whether the message in the editorial would be moderated, in consequence.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.

References

1Sathyanarayana Rao TS, Andrade C. A possible role for ketamine in suicide prevention in emergency and mainstream psychiatry. Indian J Psychiatry 2017;59:259-61.
2Bartoli F, Riboldi I, Crocamo C, Di Brita C, Clerici M, Carrà G, et al. Ketamine as a rapid-acting agent for suicidal ideation: A meta-analysis. Neurosci Biobehav Rev 2017;77:232-6.
3Larkin GL, Beautrais AL. A preliminary naturalistic study of low-dose ketamine for depression and suicide ideation in the emergency department. Int J Neuropsychopharmacol 2011;14:1127-31.
4Larkin GL, Beautrais AL. A preliminary naturalistic study of low-dose ketamine for depression and suicide ideation in the emergency department. Int J Neuropsychopharmacol 2017;20:611.