Year : 2021  |  Volume : 63  |  Issue : 2  |  Page : 208--209

Diamond Gardner syndrome in a male: A case report

Ranveer Singh1, Rachit Sharma1, Vikas Pathania2, Bharat Khadka1,  
1 Department of Psychiatry, Command Hospital (Southern Command), Pune, Maharashtra, India
2 Department of Dermatology, Command Hospital (Southern Command), Pune, Maharashtra, India

Correspondence Address:
Rachit Sharma
Department of Psychiatry, Command Hospital (Southern Command), Pune, Maharashtra

How to cite this article:
Singh R, Sharma R, Pathania V, Khadka B. Diamond Gardner syndrome in a male: A case report.Indian J Psychiatry 2021;63:208-209

How to cite this URL:
Singh R, Sharma R, Pathania V, Khadka B. Diamond Gardner syndrome in a male: A case report. Indian J Psychiatry [serial online] 2021 [cited 2021 Jun 17 ];63:208-209
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Gardner–Diamond syndrome is a rare autoimmune vasculopathy of little known etiology, which typically occurs in middleaged females; characterized by atraumatic painful ecchymotic lesions following emotional and psychological distress. The condition is characterized by recurrent selflimiting episodes of spontaneously appearing painful ecchymoses.[1],[2] Usually, the investigations including bleeding time, clotting time, capillary fragility, and prothrombin concentration are not contributory. Autosensitization of patients to their own red blood cells, plays an important role in the pathogenesis.[3]

This 32-year-old male industrial worker was referred to Psychiatry OPD by Dermatologist for the evaluation of anxiety symptoms. History revealed premorbidly anxious avoidant and dependent personality traits with free floating anxiety symptoms for past 6 months causing significant distress and dysfunction. Furthermore, there was history of sudden appearance of painful ecchymotic patches over body in stressful, insoluble and conflicting situations [Figure 1]. These patches were self-limiting in nature and used to remit spontaneously in the next 7–10 days. There was no prior history of trauma, bleeding diathesis, any significant drug or family history. Other clinical examination was unremarkable. Serial reviews revealed anxiety cognitions and catastrophization. His hematological and biochemical investigations including platelet size and morphology, coagulation profile and antinuclear antibodies were within normal limits. A hematology and dermatology consult was taken and intradermal injection of 0.1 ml autologous washed erythrocytes on flexure aspect of the left forearm caused an ecchymotic patch of approximately 2 cm diameter in 2 h [Figure 2]. Based on the above findings, he was diagnosed with Diamond–Gardner syndrome and was started on tablet amitryptiline 75 mg and short course of benzodiazepines. After 3 weeks, he was enrolled in psychotherapy in the form of psychoeducation about illness and cognitive behaviour therapy (CBT) for anxiety. During regular monthly follow-up period, there was no re-emergence of such symptoms.{Figure 1}{Figure 2}

Diamond Gardner syndrome is one of the classical examples of psychocutaneous disorders. It was earlier thought to be exclusively an illness of female as there were very few case reports of male being afflicted by this disease.[4],[5] With increase in number of cases being reported, it should be considered in the differential diagnosis of recurrent painful purpura even in males.

Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form, the patient has given his consent for his images and other clinical information to be reported in the journal. The patient understands that his name will not be published and due efforts will be made to conceal his identity.

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