Indian Journal of PsychiatryIndian Journal of Psychiatry
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   1998| July-Sept  | Volume 40 | Issue 3  
    Online since May 14, 2010

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Psychiatric Diagnosis of Self Poisoning Cases : A General Hospital Study
RB Galgali, Sanjeev Rao, MV Ashok, P Appaya, K Srinivasan
July-Sept 1998, 40(3):254-259
Attempted suicide due to overdose with toxic chemicals and medication is on the rise. Among the survivors of attempted suicide, the most frequent psychiatric diagnosis when analysed post hoc, seems to be reactive depression and personality disorders. We conducted a retrospective study of patients who attempted suicide by self poisoning in a teaching general hospital. The most frequent LCD. 10 psychiatric diagnosis among them was adjustment disorder. Insecticides containing organophosphorous compounds were the most frequent self administered toxic compound. The reported stressful factors were also studied.
[ABSTRACT]   Full text not available  [PDF]  [PubMed]
  1,332 94 -
Comorbidity in Children with Mental Retardation
Christoday R. J Khess, Indrani Dutta, Indrani Chakrabarty, Piyali Bhattacharya, Jnanamay Das, Sonia Kothari
July-Sept 1998, 40(3):289-294
This study was conducted in the child psychiatry unit of a tertiary psychiatric hospital. 60 patients diagnosed to have mental retardation according to ICD-10 (WHO, 1992) criteria constituted the study sample. A psychiatric disorder was present in 56.17% of the cases, and a medical disease was present in 35.0%. Only 13.3% cases had both a psychiatric as well as medical illness. Patients with a psychiatric illness were found to have a lesser degree of retardation. The commonest psychiatric disorder observed was behavioural and emotional disorders, while the commonest medical illness found was epilepsy. Patients with a medical illness were found to have a negative family history for a mental illness, and were much younger at the first consultation compared to the patients with a psychiatric illness. The above findings have been discussed, with emphasis on issues like dual diagnosis and diagnostic overshadowing.
[ABSTRACT]   Full text not available  [PDF]  [PubMed]
  693 120 -
Geropsychiatric Morbidity in Rural Uttar Pradesh
SC Tiwari, Shrikant Srivastava
July-Sept 1998, 40(3):266-273
In a specific geographical area an estimate of prevalence of psychiatric morbidility was done. The sample was divided into geriatric population-psychiatrically ill and non-ill, and non-geriatric psychiatrically ill-field based population; the last group was compared with a similar hospital based sample. The total prevalence of psychiatric illness in geriatric group was 42.21%, and neurotic depression, MDP-depressed and anxiety state were most prevalent. To no single factor could be a definitive role, such as diagnostic, etiological, therapeutic or preventive, could be attributed.
[ABSTRACT]   Full text not available  [PDF]  [PubMed]
  702 70 -
Serum Lipids : New Biological Markers in Depression?
Abdul Khalid, Narottam Lal, JK Trivedi, PK Dalal, OP Asthana, JS Srivastava, Asif Akhtar
July-Sept 1998, 40(3):217-223
Several studies suggest that a low cholesterol concentration is associated with depression. The authors sought to determine whether an association exists between serum lipid concentrations and depression. 28 drug-naive patients of major depression diagnosed according to DSMlll- R criteria were included in the study and severity of depression was measured on Hamilton Rating Scale for Depression. Suicidal intent was assessed on Suicidal Intent Questionnaire. 28 normal healthy controls were selected and matched for age, sex and body-mass index with the depressives. Serum lipid estimations were done in each subject after 12 hours overnight fasting. The main finding of the study is that total serum cholesterol, serum triglycerides and serum LDL cholesterol are decreased while serum HDL cholesterol is increased in depression and these changes were more marked in depressed subjects with definite suicidal intent. On regression analysis, total serum cholesterol was the most important predictive variable of the severity of depression.
[ABSTRACT]   Full text not available  [PDF]  [PubMed]
  657 88 -
Dr. Parmanand Kulhara's Response
Parmnand Kulhara
July-Sept 1998, 40(3):305-305
Full text not available  [PDF]  [PubMed]
  678 38 -
Psychiatric Profiles in Medical-Surgical Populations : Need for A Focused Approach to Consultation-Uaison Psychiatry In Developing Countries
Ajit Avasthi, Pratap Sharan, Parmanand Kulhara, Savita Malhotra, Vijoy K Varma
July-Sept 1998, 40(3):224-230
Aim To study the profile of psychiatric disorders in medical-surgical inpatients so that subpopulations with particular mental health care needs could be identified. Findings: a retrospective analysis of 1245 referrals seen over seven years showed that psychiatric profiles in referrals from different sub-populations divided according to age, gender, source of referral and medical-surgical diagnosis, were quite dissimilar. It was felt that non-recognition of specific needs of these client groups had led to low referral rates (0.65%), and to referral practices wherein the needs of the consultee (referral for disturbed behaviour) and the consultant (management by pharmacologic agents) and certain social biases (low referrals for suicide attempts) had taken precedence over the requirements of optimal management of the cases. Implications : Financial and manpower constraints limit the advocacy for a superspecialist orientation, as a policy in India. It is recommended that while continuing with the provision of general consultation services, psychiatrists should acquire expertise in areas of C-L work, which fit in with their area of interest in general psychiatry.
[ABSTRACT]   Full text not available  [PDF]  [PubMed]
  627 87 -
Socio -Demography, Personality Profile and Academic Performance of Various Categories of Medical Students
RC Jiloha, Jugal Kishore
July-Sept 1998, 40(3):231-239
To compare the Scheduled Caste (SC) & Scheduled Tribe (ST) students with general students regarding their school and family background, personality profile and personal problems, a stratified systematic sample of 261 medical students was taken who filled up their individual set of questionnaires consisting of semistructured sociodemographic proforma, Personality Trait Inventory (PTI) and Students Personal Problems Index. Statistically significant differences were observed when schooling, family income, parents education and occupation and academic performance of general, SC and ST students were compared. Although no statistical differences on personality trait were observed, on activity and cyclothymic personality trait SC and ST students scored less, whereas, they scored more on depressive tendency, emotional instability and social desirability personality traits. The personal problems were different in three groups and also the number of attempts made to pass their professional examinations. Intervention measures have been suggested.
[ABSTRACT]   Full text not available  [PDF]  [PubMed]
  559 77 -
Neuropsychological Rehabilitation of Alchoholics : A Preliminary Report
Grace Mathai, Shobini L Rao, PS Gopinath
July-Sept 1998, 40(3):280-288
Alcoholism is associated with impairment of information processing attention, memory and concept formation, which hamper the patients response to psychotherapy aimed at treating alcoholism. We improved cognitive functioning in abstinent alcoholics through cognitive retraining. Eight detoxified male alcoholics, comparable on age, education, marital status, medication and years of alcohol consumption were assigned, four each to the treatment and control groups. Cognitive retraining given to the treatment group improved attention, information processing, memory, planning and reasoning. Daily, individual, one hour sessions were conducted for six weeks. Patients in the control groups were seen weekly once and counselled if necessary. In the treatment group, significant improvement of information processing, memory, and reduction of neuropsychological deficits resulted from retraining. Control group showed no changes in cognitive function. Family functioning and long term abstinence were not influenced by cognitive retraining. Neuropsychological rehabilitation is effective in improving cognitive deficits of abstinent alcoholics.
[ABSTRACT]   Full text not available  [PDF]  [PubMed]
  561 72 -
Maked Thrombocyte Count Variations without Agranuloctosis Due to Clozapine
V Savithasri Eranti, Santosh K Chaturvedi
July-Sept 1998, 40(3):300-302
We report here a serendipitous observation of marked variations in blood thrombocyte count without agranulocytosis in a patient being treated with clozapine. Possible mechanisms of this thrombocytopenia and thrombocytosis related to clozapine are discussed, raising questions regarding monitoring of platelet counts alongwith granulocyte counts to prevent serious complications as a result of thrombocytosis or thrombocytopenia.
[ABSTRACT]   Full text not available  [PDF]  [PubMed]
  588 39 -
Clinical Profile of Patients Attending A Prison Psychiatric Clinic
RK Chadda, Amarjeet
July-Sept 1998, 40(3):260-265
Psychiatric morbidity is higher in prison inmates as compared to that in general population but treatment facilities are often inadequate. The present work reports the profile of psychiatric patients seen in a jail hospital over a period of three months. The jail had about 9000 inmates. Psychiatric services consisted of weekly visit by a psychiatrist. Seventy two male inmates were seen during the period of study. Most of them (80%) were undertrials. Diagnosis included schizophrenia, depression, bipolar disorder, anxiety disorders, and malingering. Stress of imprisonment contributed to the illness only in a small percentage of patients. Among the admitted patients, jail environment interfered with improvement. Frequent relapses were noted among the improved schizophrenic patients when transferred back to the jail. The study emphasises the need for improving the conditions in jail and developing prison psychiatric units to be managed by psychiatrists.
[ABSTRACT]   Full text not available  [PDF]  [PubMed]
  547 77 -
Risperidone in Indian Patients with Schizophrenia
AK Agarwal, V.S.P Bashyam, SM Channabasavanna, HS Dhavale, M. A. M Khan, Sumant Khanna, PV Pradhan, M Katiyar, R Rajkumar, Faiz R Niazi, RK Jalali, R Gowrishankar, SK Mishra, OP Sood
July-Sept 1998, 40(3):247-253
Conventional antipsychotic agents are not effective against negative symptoms of schizophrenia and are also noted for their extrapyramidal side effects. Risperidone is a noval antipsychotic agent whose dual antagonism of dopamine and serotonin receptors is believed to underlie its efficacy against negative symptoms and the low incidence of extrapyramidal side effects. An open, non-comparative study of seven weeks duration was performed to evaluate risperidone in the treatment of schizophrenia in Indian patients. Previous antipsychotic therapy was discontinued for a week before risperidone therapy was initiated. At the end of six weeks of risperidone therapy, clinical improvement (≥ 20% reduction in total score on positive and negative syndrome scale for schizophrenia (PANSS;; was shown by 128 (87.7%) of the 146 evaluable patients. Statistically significant reduction (p <0.05) occurred in the total score of this scale and in the subscale scores for positive, negative and general psychopathology symptoms and in the clinical global impression severity score. The number of patients with adverse experiences were 108 (65.5%) at baseline and 120 (72.7%) at the end of risperidone therapy. Extrapyramidal symptoms, seen in 65 (39.4%) patients compared to 22 (13.3%) patients at baseline, were largely mild to moderate in intensity.
[ABSTRACT]   Full text not available  [PDF]  [PubMed]
  573 49 -
Neurobiological Characterization of Bipolar Affective Disorders : A Focus on Tardive Dyskinesia and Soft Neurological Signs in Relation to Serum Dopamine Beta Hydroxylase Activity
Utpal Goswami, S Basu, U Khastgir, Unnati Kumar, R Chandrasekaran, BN Gangadhar, Rajesh Sagar, JS Bapna, SM Channabasavanna, Brain P Moore, I Nicol Ferrier
July-Sept 1998, 40(3):201-211
In this study, the prognostic determinants were investigated involving bipolar patients classified into two groups-one with favourable course and outcome, and the other with clearly unfavourable prognosis, based on certain recommended criteria, with intermediate prognosis were excluded. As compared to the poor prognosis group, the good prognosis group had lower social dysfunctions, lower ratings on psychopathotogy fewer indicators of neurodysfunction in form of neurological soft signs (NSS) and tardive dyskinesia (TD). The poor prognosis group was characterized by: (i) older age at onset; (ii) more manic than depressive episodes (5:1) and (HI) lower levels of serum dopamine-H-hydroxylase activity (DBH). The association between poor prognosis' bipolar disorder having neuroleptic intolerance (TD and NSS) with low serum DBH, suggests that it is genetically governed. Further research in this direction seems in order, particularly the follow up of first episode manic disorders.
[ABSTRACT]   Full text not available  [PDF]  [PubMed]
  545 64 -
Treatment of Age-Related Cognitive Decline with a Herbal Formulation : A Double-Blind Study
Chittaranjan Andrade, Srikante Gowda, SK Chaturvedi
July-Sept 1998, 40(3):240-246
There is little published research in mainstream Indian journals of the clinical psychotropic properties of herbal medicines. The present study therefore evaluated the psychotropic effects of Memorin (from a pharmaceutical house based at Maharashtra), a herbal formulation. Subjects with DSM-IV age-related cognitive decline were randomized to receive Memorin (n=22) or placebo (n=23) for three months. Before and after treatment, all subjects completed a battery of neuropsychological tests that assessed visual and verbal memory, visuospatial skills, and perceptuomotor functioning Subjects and rater were alike blind to treatment group. The results revealed that in the Memorin group, on most tests significant improvement in performances were observed after treatment; improvement in many of the memory tasks was however confined to males; age did not significantly influence the results. In contrast, in placebo-treated subjects there was little therapeutic gain. It is concluded that irrespective of the subject's actual age, Memorin may benefit elderly persons, particularly males, who experience age-related cognitive decline.
[ABSTRACT]   Full text not available  [PDF]  [PubMed]
  522 63 -
Psychological Factors in Psoriasis
S Chaudhury, AL Das, Ranjan T John, P Ramadasan
July-Sept 1998, 40(3):295-299
This study compares the levels of anxiety, depression, alexithymia and stressful life events in 30 consecutive patients of psoriasis with equal number of age and sex matched normal controls, patients with fungal infections and patients with neurosis, Sinha's anxiety scale, Hamilton's depression rating scale, Toronto alexithymia scale and the presumptive stressful life events scale were used to measure anxiety, depression, alexithymia and stressful life events respectively Analysis revealed that patients with psoriasis were significantly more anxious and depressed, obtained significantly higher alexithymia scores and had significantly more stressful life events as compared to normal subjects and patients with fungal skin infection. Psoriatics were significantly less anxious and depressed as compared to neurosis patients. Six patients with psoriasis were dependent on alcohol. Measures to reduce anxiety and depression and reduction of alcohol intake will not only improve subjective wellbeing of psoriasis patients but may also prevent relapses.
[ABSTRACT]   Full text not available  [PDF]  [PubMed]
  484 86 -
Rejection of Chronic Schizophrenic Patients : Some Preliminary Observations from Kerala
L. Sam S Manickam, Satheesh R Satheesh Chandran
July-Sept 1998, 40(3):274-279
A study was conducted on 57 relatives (34 male and 23 female) of 57 (32 male and 25 female) schizophrenic patients in Kerala. The rejection response was found to be related to gender of patients and relatives, being significantly higher in males. The test reliability alpha of the Patient Rejection Scale was found to be 0.93 and it is higher than English and German version of the scale. Compared to the German and New York sample, the present sample tend to have high rejection feeling.
[ABSTRACT]   Full text not available  [PDF]  [PubMed]
  526 33 -
Relationship Between Lower Serum Cholesterol Level and Psychiatric Disorders
Debasish Sanyal, Jharna Basu, Kalyan Banerjee, Ranjita Biswas
July-Sept 1998, 40(3):212-216
The study applies the General Health Questionnaire (GHQ-60) to 50 consecutive patients attending Psychiatry-O.P.D., Medical College, Calcutta provided they meet the inclusion and exclusion criteria. Subjects were between 15 to 55 years, literate, and did not have any physical disease or condition specially those which can alter serum cholesterol level. Every patient was physically examined and interviewed. Subjects scoring less than 11 on GHQ were taken to have no psychiatric disease. Serum cholesterol level of these subjects was contrasted with subjects scoring 11 or more on GHQ, who were considered to have psychiatric diagnosis. The study showed that male psychiatric patients had statistically significant lower serum cholesterol than normal subjects while no significant lowering was observed in female psychiatric patients.
[ABSTRACT]   Full text not available  [PDF]  [PubMed]
  480 36 -
Burden of Care in Parents of Children Suffering from Haematological Malignancies
MV Ashok, Vijaya Raman
July-Sept 1998, 40(3):304-305
Full text not available  [PDF]  [PubMed]
  273 21 -
High Dose Fluoxetine in Obsessive Compulsive Disorder
Vivek Agarwal
July-Sept 1998, 40(3):304-304
Full text not available  [PDF]  [PubMed]
  265 27 -
Contemporary Issues in Management of Impotence
JK Trivedi
July-Sept 1998, 40(3):199-200
Full text not available  [PDF]  [PubMed]
  249 37 -
A Textbook of Psychoanalitically Oriented Psychotherapy : Theory and Technique
Pratap Sharan
July-Sept 1998, 40(3):306-306
Full text not available  [PDF]
  238 40 -
Who Needs Psychiatry, Who Cares For Psychiatry?
C Shamasundar
July-Sept 1998, 40(3):303-305
Full text not available  [PDF]  [PubMed]
  231 28 -